Methandienone has the effect of decreasing the steroid’s affinity for sex hormone binding globulin. As a result, methandrostenolone is significantly more active than an equivalent quantity of testosterone, resulting in rapid growth of muscle tissue. However, the concomitant elevation in estrogen levels – a result of the aromatization of methandrostenolone – results in significant water retention. Hence, do not forget to perform blood works and use an aromatase inhibitor. In summary, this is a very good drug, and a potent tool for quick gains or retaining gains when used properly and safely.